Melatonin treatment in an institutionalised child with psychomotor retardation and an irregular sleep-wake pattern.
نویسندگان
چکیده
An institutionalised 13 year old girl with psychomotor retardation suffered from an irregular sleep-wake pattern. Multiple measurements of urinary sulphatoxy-melatonin (aMT6) concentrations were abnormally low, without any significant day-night differences. Administration of exogenous melatonin (3 mg) at 18:00 resulted in increased nocturnal urinary aMT6 concentrations and improvements in her sleep-wake pattern. Melatonin may help disabled children suffering from sleep disorders.
منابع مشابه
The therapeutics of melatonin: a paediatric perspective.
The production of melatonin by the pineal gland and its functions are considered, and then its possible uses in the treatment of children. Institutionalized children, and those with severe learning disorders, often have irregular sleep-wake patterns, and there is evidence that melatonin can result in improvement to the benefit of both the child and the carers. The affected children can become l...
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ورودعنوان ژورنال:
- Archives of disease in childhood
دوره 79 1 شماره
صفحات -
تاریخ انتشار 1998